Estimating enrichment of repetitive elements from high-throughput sequence data
نویسندگان
چکیده
منابع مشابه
Learning quantitative sequence-function relationships from high-throughput biological data
Understanding the transcriptional regulatory code, as well as other types of information encoded within biomolecular sequences, will require learning biophysical models of sequence-function relationships from high-throughput data. Controlling and characterizing the noise in such experiments, however, is notoriously difficult. The unpredictability of such noise creates problems for standard like...
متن کاملHigh-throughput DNA sequence data compression
The exponential growth of high-throughput DNA sequence data has posed great challenges to genomic data storage, retrieval and transmission. Compression is a critical tool to address these challenges, where many methods have been developed to reduce the storage size of the genomes and sequencing data (reads, quality scores and metadata). However, genomic data are being generated faster than they...
متن کاملEstimating the ratio of CD4+ to CD8+ T cells using high-throughput sequence data.
Mature T cells express either CD8 or CD4, defining two physiologically distinct populations of T cells. CD8+ T cells, or killer T-cells, and CD4+ T cells, or helper T cells, effect different aspects of T cell mediated adaptive immunity. Currently, determining the ratio of CD4+ to CD8+ T cells requires flow cytometry or immunohistochemistry. The genomic T cell receptor locus is rearranged during...
متن کاملDevelopment of a computational strategy to compare repetitive element enrichment between experimental conditions from high-throughput sequencing datasets
Repetitive and transposable elements comprise more than half of the human genome and play diverse roles in many biological processes. Mobile elements including retrotransposons are implicated in the organization of the epigenetic landscape, the progression of tumorigenesis, and the enhancement of genetic diversity. Despite the importance of repetitive and transposable elements these sequences a...
متن کاملdegradation of oil impregnated paper insulation under influence of repetitive fast high voltage impulses
در طی سالهای اخیراستفاده ازمنابع انرژی تجدید پذیر در شبکه های مدرن بنا به دلایل زیست محیطی و اقتصادی به طور گسترده استفاده شده است همچون نیروگاههای بادی و خورشیدی .ولتاژتولیدی این نیروگاهها اغلب به فرم dc می باشد وادوات الکترونیک قدرت به عنوان مبدل و پل بین شکل موج dc وac استفاده می شوند.این پروسه باعث ایجاد پالسهایی برروی شکل موج خروجی می شود که می تواند وارد تجهیزات قدرت همچون ترانسفورماتور ی...
15 صفحه اولذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Genome Biology
سال: 2010
ISSN: 1465-6906
DOI: 10.1186/gb-2010-11-6-r69